About study
Bachelor 4th grade
Biologically compounds are known to be composed only of one of the d and l enantiomers. For example, L-amino acid and D-sugar. This is called homochirality, Such phenomenon is common to all life on the earth and it is considered that grasping the process of acquiring homochirality by bio-related substances is thought to grasp the origin of life and it attracts a lot of attention. Circularly polarized light, quartz, chiral crystals of achiral compounds, spontaneous absolute asymmetric synthesis, etc. have been proposed as the origin of homochirality. However, since the enantiomeric excess (ee) induced from the origin of these asymmetries is negligible, some asymmetric amplification and proliferation mechanism is required to achieve homochirality. I focused on the quartz which is one of the origins of homochirality, and I was doing experiments. Quartz is chiral inorganic crystals with mirror images on both sides, and examples have been reported in which asymmetric reactions are caused by chiral surfaces. I have been experimenting to find the stereocorrelation of aminonitrile using quartz as an asymmetric source, but no results were obtained in one year. However, it was discovered that the quartz has an influence on the formation of aminonitrile. The rate at which aminonitrile is formed increases in the presence of quartz. I went to graduate school and thought about continuing my research, but now I am researching nanofiber because I cannot continue because of various circumstances.
Master
The current theme is to cause the change in activity due to the contact area of the enzyme on the fiber. It is reported that the activity of the enzyme increases with its contact area. Therefore, I thought that by adding gold nanoparticles on or in the fiber, the surface of the fiber becomes uneven, and the activity is increased by adsorbing the enzyme there. However, since gold nanoparticles are not well dispersed in solution, experimental operation is under consideration. Moreover, I am planning to perform experiments electrochemically. I thought that the same situation could be created by forming a self-assembled monolayer (SAM) on the gold electrode and putting gold nanoparticles on the SAM.
Biologically compounds are known to be composed only of one of the d and l enantiomers. For example, L-amino acid and D-sugar. This is called homochirality, Such phenomenon is common to all life on the earth and it is considered that grasping the process of acquiring homochirality by bio-related substances is thought to grasp the origin of life and it attracts a lot of attention. Circularly polarized light, quartz, chiral crystals of achiral compounds, spontaneous absolute asymmetric synthesis, etc. have been proposed as the origin of homochirality. However, since the enantiomeric excess (ee) induced from the origin of these asymmetries is negligible, some asymmetric amplification and proliferation mechanism is required to achieve homochirality. I focused on the quartz which is one of the origins of homochirality, and I was doing experiments. Quartz is chiral inorganic crystals with mirror images on both sides, and examples have been reported in which asymmetric reactions are caused by chiral surfaces. I have been experimenting to find the stereocorrelation of aminonitrile using quartz as an asymmetric source, but no results were obtained in one year. However, it was discovered that the quartz has an influence on the formation of aminonitrile. The rate at which aminonitrile is formed increases in the presence of quartz. I went to graduate school and thought about continuing my research, but now I am researching nanofiber because I cannot continue because of various circumstances.
Master
The current theme is to cause the change in activity due to the contact area of the enzyme on the fiber. It is reported that the activity of the enzyme increases with its contact area. Therefore, I thought that by adding gold nanoparticles on or in the fiber, the surface of the fiber becomes uneven, and the activity is increased by adsorbing the enzyme there. However, since gold nanoparticles are not well dispersed in solution, experimental operation is under consideration. Moreover, I am planning to perform experiments electrochemically. I thought that the same situation could be created by forming a self-assembled monolayer (SAM) on the gold electrode and putting gold nanoparticles on the SAM.